(213f) Artificial Water Channels-Toward Biomimetic Membranes for Desalination
AIChE Annual Meeting
2022
2022 Annual Meeting
Separations Division
Honorary Session for Prof. Suzana Nunes I
Monday, November 14, 2022 - 5:00pm to 5:20pm
This lecture discusses the incipient development of the first artificial water channels systems. We
include only systems that integrate synthetic elements in their water selective translocation unit. Therefore, we
exclude peptide channels because their sequences derive from the proteins in natural channels. We review
many of the natural systems involved in water and related proton transport processes. We describe how these
systems can fit within our primary goal of maintaining natural function within bio-assisted artificial systems. In
the last part, we present several inspiring breakthroughs from the last decade in the field of biomimetic artificial
water channels. All these examples demonstrate how the novel interactive water-channels can parallel
biomolecular systems. At the same time these simpler artificial water channels offer a means of understanding
water structures useful to understanding many biological scenarios. Moreover, they can be used for the
preparation of highly selective membranes for desalination.
[1] M. Barboiu and A. Gilles, Acc. Chem. Res. 2013, 46, 2814â2823.
[2] M. Barboiu, Angew. Chem. Int. Ed. 2012, 51, 11674-11676.
[3] Y. Le Duc, et al., Angew. Chem. Int. Ed. 2011, 50(48), 11366-11372.
[4] E. Licsandru, et al., J. Am. Chem. Soc., 2016, 138, 5403-5409.
[5] M. Barboiu, Chem. Commun., 2016, 52, 5657- 5665.
[6] I. Kocsis, et al. Science Adv. 2018, 4, eaao5603.
[7] M. Di Vincenzo, A. Tiraferri, V.-E. Musteata, S.Chisca, R.Sougrat, L.-B. Huang, S. P. Nunes, M. Barboiu,
Nat. Nanotechnol. 2021, 16, 190-196.
[8] M. Di Vincenzo, et al. Proc. Natl. Acad. Sci. USA, 2021, 118(37), e2022200118
[9] L.-B. Huang, M. Di Vincenzo, M. GöktuÄ Ahunbay, A. van der Lee, D. Cot, S. Cerneaux, G. Maurin, and M.
Barboiu, J. Am. Chem. Soc. 2021, 143, 14386-14393
include only systems that integrate synthetic elements in their water selective translocation unit. Therefore, we
exclude peptide channels because their sequences derive from the proteins in natural channels. We review
many of the natural systems involved in water and related proton transport processes. We describe how these
systems can fit within our primary goal of maintaining natural function within bio-assisted artificial systems. In
the last part, we present several inspiring breakthroughs from the last decade in the field of biomimetic artificial
water channels. All these examples demonstrate how the novel interactive water-channels can parallel
biomolecular systems. At the same time these simpler artificial water channels offer a means of understanding
water structures useful to understanding many biological scenarios. Moreover, they can be used for the
preparation of highly selective membranes for desalination.
[1] M. Barboiu and A. Gilles, Acc. Chem. Res. 2013, 46, 2814â2823.
[2] M. Barboiu, Angew. Chem. Int. Ed. 2012, 51, 11674-11676.
[3] Y. Le Duc, et al., Angew. Chem. Int. Ed. 2011, 50(48), 11366-11372.
[4] E. Licsandru, et al., J. Am. Chem. Soc., 2016, 138, 5403-5409.
[5] M. Barboiu, Chem. Commun., 2016, 52, 5657- 5665.
[6] I. Kocsis, et al. Science Adv. 2018, 4, eaao5603.
[7] M. Di Vincenzo, A. Tiraferri, V.-E. Musteata, S.Chisca, R.Sougrat, L.-B. Huang, S. P. Nunes, M. Barboiu,
Nat. Nanotechnol. 2021, 16, 190-196.
[8] M. Di Vincenzo, et al. Proc. Natl. Acad. Sci. USA, 2021, 118(37), e2022200118
[9] L.-B. Huang, M. Di Vincenzo, M. GöktuÄ Ahunbay, A. van der Lee, D. Cot, S. Cerneaux, G. Maurin, and M.
Barboiu, J. Am. Chem. Soc. 2021, 143, 14386-14393