(93a) Delivering on the Promise of Synthetic Biology
AIChE Annual Meeting
2024
2024 AIChE Annual Meeting
Separations Division
Bioseparations: Materials and Molecules I
Monday, October 28, 2024 - 8:00am to 8:30am
Amyris is a vertically integrated industrial biotechnology company that has successfully commercialized 15 unique fermentation-derived molecules over the past 16 years. These molecules span a range of physical and chemical properties, from oils to highly-water soluble species to extremely insoluble compounds, and they are ingredients in a diverse array of final products, including fuels, fragrances, flavors, and pharmaceutical excipients. This variety of products and applications has enabled Amyris to develop a flexible and broad downstream process separation and purification toolkit. Some of the most challenging molecules to develop are those that are intracellular or those that are extremely toxic to the host.
Despite the challenges posed by intracellular and highly toxic molecules, Amyris has pursued the development of these products due to their potential value and impact. This talk will describe the process approaches the company has taken to deliver these challenging molecules, as well as the specific challenges encountered, and the lessons learned along the way.
The authors would like to acknowledge and thank BioMADE and Schmidt futures for their continued support of projects discussed in this talk.