Conference Program
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Wednesday, December 4th |
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| 7:00 AM | 9:00 AM | Badge Pick-up/Check in |
| 8:55 AM | 9:00 AM | Welcoming Remarks: Vincent Noireaux and William Blake |
| 9:00 AM | 10:00 AM | Keynote Speaker: Freeze-Dried, Cell-Free Synthetic Biology James J. Collins, Massachusetts Institute of Technology |
| 10:00 AM | 10:30 AM | Break |
| 10:30 AM | 12:00 PM | Session 1: Diagnostics and Circuits Session Chair: Elizabeth Strychalski, NIST |
| 10:30 AM | 11:00 AM | Invited Speaker: Using Cell-Free Systems to Develop and Deploy Biosensors That Meet Army Needs Patricia Buckley, CCDC Chemical Biological Center |
| 11:00 AM | 11:20 AM | Metabolic Perceptrons for Neural Computing in Cell Free Systems Manish Kushwaha, INRA |
| 11:20 AM | 11:40 AM | Persia for Direct Fluorescence Measurements of Transcription,Translation, and Enzyme Activity in Cell-Free Systems Peter Carr, MIT Lincoln Laboratory |
| 11:40 AM | 12:00 PM | Cell Free Operating Systems for Diagnostics Andrew Ellington, University of Texas at Austin |
| 12:00 PM | 12:10 PM | ARPA E announcement |
| 12:10 PM | 1:10 PM | Lunch |
| 1:10 PM | 3:00 PM | Session 2: Diagnostics and Circuits Session Chair: Melissa Takahashi, Cal State Northridge |
| 1:10 PM | 1:40 PM | Invited Speaker: A Measurement Foundation for the Future of Cell-free Systems Jane Romantseva, National Institute of Standards and Technology |
| 1:40 PM | 2:00 PM | Tackling Global Health Challenges with Cell-Free Synthetic Biology: New Technologies for Rapid, on-Demand Water Quality Monitoring Julius Lucks, Northwestern University |
| 2:00 PM | 2:20 PM | Expanding the Scope of Cell-Free Diagnostics: Equipment-Free Quantification of Biomarkers in Human Serum Monica McNerney, Georgia Institute of Technology |
| 2:20 PM | 2:40 PM | Identification of Additive Formulations for Enhanced Shelf-Life and Productivity of E. coli Cell Extracts Javin P. Oza, California Polytechnic State University, San Luis Obispo |
| 2:40 PM | 3:00 PM | INSPECTR - A breakthrough platform for cell-free molecular diagnostics Paul Carlson, Sherlock Biosciences |
| 3:00 PM | 3:30 PM | Break |
| 3:30 PM | 5:00 PM | Session 3: Building Biology Session Chair: Sebastian Maerkl, EPFL |
| 3:30 PM | 3:50 PM | Accessible and Easy-to-Use Educational Tools to Teach Molecular and Synthetic Biology Using Freeze-Dried, Cell-Free Technology Ally Huang, miniPCR |
| 3:50 PM | 4:10 PM | Rapidly Prototyping CRISPR Biology and Technologies with an All-E. coli Txtl System Chase Beisel, Helmholtz Institute for RNA-based Infection Research |
| 4:10 PM | 4:30 PM | Artificial Cells on a Chip Roy Bar-Ziv, Weizmann Institute of Science |
| 4:30 PM | 5:00 PM | Invited Speaker: Cell-free Cells Kate Adamala, University of Minnesota |
| 5:00 PM | 6:30 PM | Reception, Poster Session |
Thursday, December 5th |
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| 8:00 AM | 10:00 AM | Badge Pick-up/Check in |
| 8:30 AM | 9:00 AM | Breakfast |
| 9:00 AM | 10:00 AM | Keynote Speaker: Marileen Dogterom, TU Delft |
| 10:00 AM | 10:20 AM | Break |
| 10:20 AM | 12:00 PM | Session 4: Circuits & Measurement Session Chair: Filippo Caschera, LenioBio |
| 10:20 AM | 10:50 AM | Invited Speaker: Paul Freemont, Imperial College London |
| 10:50 AM | 11:10 AM | A Direct Gene Circuit - Electronic Interface for Cell-Free Synthetic Biology Keith Pardee, University of Toronto |
| 11:10 AM | 11:30 AM | Cell-Free Gene Expression in Synthetic Multicellular Structures and Organelles Friedrich C. Simmel, TU Munich |
| 11:30 AM | 12:00 PM | Invited Speaker: Integrated Mesoscale Synthetic Regulatory Networks Build from Genelets Rebecca Schulman, Johns Hopkins University |
| 12:00 PM | 1:00 PM | Lunch |
| 1:00 PM | 3:00 PM | Session 5: Prototyping and Characterization Session Chair: Javin Oza, California Polytechnic State University |
| 1:00 PM | 1:15 PM | Geometric Control of Bio-Machine Assembly By a Genetic Program on a Chip Shirley S. Daube, Weizmann Institute of Science |
| 1:15 PM | 1:30 PM | Engineering Synthetic Organelles to Spatially Organize Biochemical Reactions in Artificial Cells and Cell-Free Systems Henrike Niederholtmeyer, University of California, San Diego |
| 1:30 PM | 1:45 AM | A Cell-Free Protein Synthesis Platform for Rapid and Quantitative Protein-Protein Interaction Analysis Andrew Hunt, Northwestern University |
| 1:45 PM | 2:00 PM | Boosting the Activity of CHO-Based Cell-Free Protein Chiara Heide, Imperial College London |
| 2:00 PM | 2:15 PM | Large Scale Active-Learning-Guided Exploration to Maximize Cell-Free Production Olivier Borkowski, Pasteur Institute, INRIA |
| 2:15 PM | 2:30 PM | Prototyping Gene Expression in a Chloroplast Cell-Free System for Plant Engineering Eszter Majer, Massachusetts Institute of Technology |
| 2:30 PM | 2:45 PM | A Cell-Free Biosynthesis Platform for Modular Construction of Protein Glycosylation Pathways Weston Kightlinger, Northwestern University |
| 2:45 PM | 3:30 PM | Break |
| 3:30 PM | 5:30 PM | Session 6: Prototyping and Characterization Session Chair: Jane Romantseva, NIST |
| 3:30 PM | 4:00 PM | Invited Speaker: Engineering Gene Regulatory Networks in Vitro Sebastian Maerkl, EPFL |
| 4:00 PM | 4:20 PM | Robust Cell Free Extract from Bacillus Subtilis to Prototype Engineered Spore Circuitry Nigel Reuel, Iowa State University |
| 4:20 PM | 4:40 PM | Metabolomic Characterization of Escherichia coli-Based Cell-Free Expression Systems for Process Optimization Mark P. Styczynski, Georgia Institute of Technology |
| 4:40 PM | 5:00 PM | Cell-Free Prototyping for CarbonSmartTMÂ solutions Alex Mueller, LanzaTech |
| 5:00 PM | 5:30 PM | Invited Speaker: Biodiscovery with Cell-Free Synthetic Biology Zachary Sun, Tierra Biosciences |
| 5:30 PM | 6:30 PM | Reception, Poster Session |
Friday, December 6th |
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| 8:00 AM | 10:00 AM | Badge Pick-up/Check in |
| 8:30 AM | 9:00 AM | Breakfast |
| 9:00 AM | 10:00 AM | Keynote Speaker: Cell-Free Synthetic Biology:Serving Society with Supernatural Processes and Products Jim Swartz, Stanford University |
| 10:00 AM | 10:30 AM | Break |
| 10:30 AM | 12:30 PM | Session 7: Manufacturing Session Chair: James Zawada, Sutro Biopharma |
| 10:30 AM | 11:00 AM | Invited Speaker: Advanced Cell Free Processing: Considerations for Commercial Production Caroline Cobb, Green Light Bio |
| 11:00 AM | 11:20 AM | Engineering a Non-Canonical Redox Cofactor System for Biocatalysis Han Li, University of California, Irvine |
| 11:20 AM | 11:40 AM | On-Demand Endotoxin-Free Production of Protein Cancer Therapeutics from Thermostable Freeze-Dried Cell-Free Protein Synthesis Reagents Bradley C. Bundy, Brigham Young University |
| 11:40 AM | 12:00 PM | Fast and Furious: Cell-Free Biomanufacturing Approaches Govind Rao, University of Maryland Baltimore County |
| 12:00 PM | 12:30 PM | Invited Speaker: Enabling Design and Manufacture of Best-in-Class Protein Therapeutics By Cell-Free Production; Concept to Clinical Trials Trevor J. Hallam, Sutro Biopharma |
| 12:30 PM | 12:45 PM | Closing Remarks |
