Mitchell Paolello

Mitchell Paolello is a PhD student at Rowan University, whose research focuses on controlling impurity incorporation in pharmaceutical crystallization. He has published works on impurity retention and is currently exploring the role of solution transport on impurity selectivity on specific crystal faces. He earned his BS in Chemical Engineering at Drexel University and has also worked as a co-op at Boehringer Ingelheim in Solid State and API Engineering. His AIChE presentation will highlight how the formation of crystalline solid solutions (CSS) can result in changes in polymorphic form stability, which provides a thermodynamic explanation for the common phenomenon in the pharmaceutical industry of so-called "disappearing polymorphs".