Shane T. Grosser

Citation name

Grosser, S. T.

Affiliation

Merck & Co. Inc.

State

NJ

Country

USA

Executive Director, Process Research & Development, Merck

Sessions chaired or co-chaired

Green Pharmaceutical Process Development and Biocatalysis

2017 Annual Meeting (ISBN: 978-0-8169-1102-8)

Innovative Technologies to Accelerate and Enhance Drug Discovery, Development, and Manufacturing

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

Authored

(754b) Improved Process Understanding Through Implementation of QbD Methodologies

2011 Annual Meeting

(26e) Development of a Biocatalytic Cascade for the Deracimization of a Racemic Alcohol

Shane T. Grosser

2017 Annual Meeting (ISBN: 978-0-8169-1102-8)

(328a) Multidimensional Dynamic Experiments in Flow As a Kinetic Platform for Data Rich Experimentation in Pharmaceutical Process Development

Brian Wyvratt

Jonathan P. McMullen

Shane T. Grosser

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(667b) Data Rich Experimentation Methods Towards Immobilized Biocatalysis for Drug Substance Manufacture

Shane T. Grosser

Jacob H. Forstater

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(621b) Online LC in Support of Data Rich Experimentation

Shane T. Grosser

Gabriel C. Graffius

Kerstin Zawatzky

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(470f) Defining the Optimal Operating Window for Pharmaceutical Reactions Using the Dynamic Response Surface Methodology for All Measured Species

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(34c) A Constrained Version of the Dynamic Response Surface Methodology for Challenging Time-Resolved Pharmaceutical Reaction Data

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(200s) Stoichiometry Identification in Pharmaceutical Reactions Using Dynamic Response Surface Methodology and Target Factor Analysis

2018 AIChE Annual Meeting (ISBN: 978-0-8169-1108-0)

(12a) Development of Multi-Enzyme Immobilized Biocatalytic Processes for Synthesis of Small Molecule APIs

2019 AIChE Annual Meeting (ISBN: 978-0-8169-1112-7)

(410b) Co-Immobilization of Enzyme Cascades Enables One-Pot Industrial Immobilized Biocatalysis

2019 AIChE Annual Meeting (ISBN: 978-0-8169-1112-7)

(342e) Reaction Kinetic Modeling and Process Optimization of Multi-Enzyme Biocatalytic Cascade Syntheses

2019 AIChE Annual Meeting (ISBN: 978-0-8169-1112-7)

(693b) Automated Platform for Experimental Execution and Model Regression of Volumetric Mass Transfer Coefficient and Vessel Characterization

Shane T. Grosser

Keith A. Mattern

2019 AIChE Annual Meeting (ISBN: 978-0-8169-1112-7)

(693a) Data-Rich Development of a Novel Biocatalytic Aerobic Oxidation across Scales

Christopher C. Nawrat

2019 AIChE Annual Meeting (ISBN: 978-0-8169-1112-7)

(601d) Islatravir Penultimate Step Crystallization: Purification of an API in the Presence of High Protein Loading from an Enzymatic Cascade

2020 Virtual AIChE Annual Meeting (ISBN: 978-0-8169-1114-1)

(414a) Data-Rich Experimentation at Merck. a Retrospective on a 6year Journey.

Shane T. Grosser

2020 Virtual AIChE Annual Meeting (ISBN: 978-0-8169-1114-1)

(515b) Machine Learning-Assisted Autonomous Reactor Characterization: Mass Transfer Coefficients for Oxidative Biocatalytic Reactions

Keith A. Mattern

Shane T. Grosser

Ajit Vikram

2022 Annual Meeting (ISBN: 978-0-8169-1118-9)

(605a) Scaleup Considerations for Solid-Phase Peptide Synthesis in Highly Dynamic Packed Beds.

2022 Annual Meeting (ISBN: 978-0-8169-1118-9)

(640b) Vision-Guided, High-Throughput Liquid-Liquid Extraction Screening

Alexandra Sun

Jon Jurica

Shane T. Grosser

2023 AIChE Annual Meeting (ISBN: 978-0-8169-1120-2)

(636b) Data-Rich Experimentation-Enabled Mass-Activated Droplet Sorting for Screening of Enzymatic Reactions

Ajit Vikram

Daniel Holland-Moritz

Eugene Kwan

Shane T. Grosser

Jeffrey Moore

2023 AIChE Annual Meeting (ISBN: 978-0-8169-1120-2)

Associated proceedings

2011 Annual Meeting

2017 Annual Meeting

2018 AIChE Annual Meeting

2019 AIChE Annual Meeting

2020 Virtual AIChE Annual Meeting

2022 Annual Meeting

2023 AIChE Annual Meeting

Other Sites & Tools

Technical Groups

Technical

Professional/Personal Growth

Societal Needs

Leadership

2025 Spring Meeting and 21st Global Congress on Process Safety

2025 AIChE Annual Meeting

Upcoming Conferences & Events

CEP: January 2025

CEP: December 2024

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Shane T. Grosser

Grosser, S. T.

Merck & Co. Inc.

NJ

USA

Sessions chaired or co-chaired

Authored

Associated proceedings